1st Faculty of Medicine Charles University 1st Faculty of Medicine Charles University Stopka Lab
lvysa 25.03.2020

Tomáš Zikmund - Helena Paszeková: Loss of ISWI ATPase SMARCA5 (SNF2H)

Loss of ISWI ATPase SMARCA5 (SNF2H) in Acute Myeloid Leukemia Cells Inhibits Proliferation and Chromatid Cohesion. Zikmund T, Paszekova H, Kokavec J, Kerbs P, Thakur S, Turkova T, Tauchmanova P, Greif PA, Stopka T. Int J Mol Sci. 2020;21(6):E2073. Published 2020 Mar 18.doi:10.3390/ijms21062073. (IF 4.183) [PubMed]


195 76 196

lvysa 14.01.2020

Tomáš Stopka: Chromatin remodeler Snf2h

The chromatin remodeler Snf2h is essential for oocyte meiotic cell cycle progression. Zhang C, Chen Z, Yin Q, Fu X, Li Y, Stopka T, Skoultchi AI, Zhang Y. Genes Dev. 2020 Jan 9. doi: 10.1101/gad.331157.119. (IF 8.998) [Pubmed


189 191

lvysa 08.01.2020

Tomáš Stopka: MDS News

Randomizovaná otevřená akademická studie: srovnání standardního podání azacytidinu oproti azacytidinu s preinkubací G-CSF u myelodysplastického syndromu vyššího rizika – interim analýza. Stopka T, Minařík Ĺ, Kulvait V, Pešta M, Schaffartziková A, Kislik G, Dusílková N, Zemanová Z, Jonášová A. Myelodysplastic Syndrome News. Listopad 2019. Ročník 7 / číslo 2. [PDF]


188

 

lvysa 24.09.2019

Tomáš Zikmund: ISWI ATPase Smarca5

ISWI ATPase Smarca5 Regulates Differentiation of Thymocytes Undergoing b-selection. Zikmund T, Kokavec J, Turkova T, Savvulidi F, Paszekova H, Vodenkova S, Sedlacek R, Skoultchi AI, Stopka T.. J Immunol. 2019 Jun 15;202(12):3434-3446. doi: 10.4049/jimmunol.1801684. Epub 2019 May 8. [PubMed] (IF 4.539) 185

186
lvysa 16.05.2019

Ľubomír Minařík: Azacitidine Switch to Lenalidomide

Azacitidine Switch to Lenalidomide Eradicated the TP53/ CDKN2A Co-Mutated Clone and Induced Long-Term Erythroid Response in Del(5q) MDS. Minarik L, Zemanova Z, Kulvait V, Dluhosova M, Jonasova A and Stopka T. Ann Hematol Oncol. 2019; 6(1): 0000. [PDF] (IF 2.219

180 181
lvysa 08.08.2018

Reputable publication in Haematologica July 2018

BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia. Srutova K, Curik N, Burda P, Savvulidi F, Silvestri G, Trotta R, Klamova H, Pecherkova P, Sovova Z, Koblihova J, Stopka T, Perrotti D, Machova Polakova K. Haematologica. 2018 Jul 26. pii: haematol.2018.193086. doi: 10.3324/haematol.2018.193086. [PubMed] (IF 9.09)

178
lvysa 04.04.2018

Anna Jonášová: Lenalidomide treatment in lower risk myelodysplastic syndromes

Lenalidomide treatment in lower risk myelodysplastic syndromes—The experience of a Czech hematology center. (Positive effect of erythropoietin±prednisone addition to lenalidomide in refractory or relapsed patients). Jonasova A, Neuwirtova R, Polackova H, Siskova M, Stopka T, Cmunt E, Belickova M, Moudra A, Minarik L, Fuchs O, Michalova K, Zemanova Z. Leukemia Research 69 (2018) 12-17. 2018 March 27. https://doi.org/10.1016/j.leukres.2018.03.015 . (IF 2.501) [PDF]

175 174
04.04.2018

Kamila Polgárová: Somatic mutation dynamics in MDS patients

Somatic mutation dynamics in MDS patients treated with azacitidine indicate clonal selection in patients-responders. Polgarova K, Vargova K, Kulvait V, Dusilkova N, Minarik L, Zemanova Z, Pesta M, Jonasova A and Stopka T. Oncotarget. 2017 Dec 6. (IF 5.168) [PDF] (B, N, H, 131)

  173 172

12.12.2017

Nina Dusílková & Petra Bašová: Plasma microRNAs in Cutaneous Lymphoma, in press IJMS

Plasma miR-155, miR-203, and miR-205 are Biomarkers for Monitoring of Primary Cutaneous T-cell Lymphomas. Dusilkova N, Basova P, Polivka J, Kodet O, Kulvait V, Pesta M, Trneny M, Stopka T. Int J Mol Sci. 2017 Oct 15;18(10). pii: E2136. doi: 10.3390/ijms18102136. [PDF] (IF: 3.226)

  126 123 125

12.12.2017

Petra Bašová: Serum microRNAs in Breast Cancer Relapse prediction, in press in IJMS

Prediction Potential of Serum miR-155 and miR-24 for Relapsing Early Breast Cancer. Basova P, Pesta M, Sochor M, Stopka T. Int J Mol Sci. 2017 Oct 10;18(10). pii: E2116. doi: 10.3390/ijms18102116[PDF] (IF: 3.226) 121

122 

17.10.2017

Juraj Kokavec: mouse model of Smarca5 in HSCs

Kokavec J, Zikmund T, Savvulidi F, Kulvait V, Edelmann W, Skoultchi AI, Stopka T. The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells. Stem Cells. 2017 Jun;35(6):1614-1623. doi: 10.1002/stem.2604. [https] (IF: 5.599)

129

04.04.2018

Hana Hušková - MS on cancer driver NOW in Oncogene

Huskova H, Ardin M, Weninger A, Vargova K, Barrin S, Villar S, Olivier M, Stopka T, Herceg Z, Hollstein M, Zavadil J, Korenjak M. Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing. Oncogene. 2017 Jul 10. doi: 10.1038/onc.2017.215. [PDF] (IF: 7.519)
  Výsledek obrázku pro Oncogene logo

 


 
17.10.2017

Karina Vargová - MS on miR-155/miR-150 network in CLL now in press in BCJ

Vargova K, Pesta M, Obrtlíkova P, Dusilkova N, Minarik L, Vargova J, Berkova A, Zemanova Z, Michalova K, Spacek M, Trneny M and Stopka T. MiR-155/miR-150 network regulates progression through the disease phases of chronic lymphocytic leukemia. Blood Cancer J. 2017 Jul 21;7(7):e585. doi: 10.1038/bcj.2017.63. [PDF] (IF: 6.126)

 

04.04.2018

Jarmila Vargová: MARCKS: new therapeutic target in MCL

Vargova J, Vargova K, Dusilkova N, Kulvait V, Pospisil V, Zavadil J, Trneny M, Klener P, Stopka T. Differential expression, localization and activity of MARCKS between mantle cell lymphoma and chronic lymphocytic leukemia. Blood Cancer J. 2016 Sep 23;6(9):e475. doi: 10.1038/bcj.2016.80. [PDF] (IF: 4.502)

Výsledek obrázku pro Blood Cancer Journal logo




ohlasy v tisku:

http://www.ctidoma.cz/zpravodajstvi-zdravi/2016-10-05-cesti-odbornici-zjistili-jak-vylecit-rakovinu-krve-26743

http://sciencemag.cz/cesti-vedci-na-stope-novym-lekum-proti-lymfomum/

17.10.2017

Tomáš Stopka : MDS news (in czech)

Využití detekce somatických mutací pro pacienty s cytopenií nejasného významu a u myelodysplastického syndromu. Stopka T. Myelodysplastic Syndrome NEWS. Ročník 5 / Číslo 1 / květen 2017. [PDF]
  138


17.10.2017

Pavel Burda: addition to BBA, collaborative project with John Strouboulis

Papageorgiou DN, Karkoulia E, Amaral-Psarris A, Burda P, Kolodziej K, Demmers J, Bungert J, Stopka T, Strouboulis J. Distinct and overlapping DNMT1 interactions with multiple transcription factors in erythroid cells: Evidence for co-repressor functions. Biochim Biophys Acta. 2016 Dec;1859(12):1515-1526. doi: 10.1016/j.bbagrm.2016.09.007. [https] (IF: 5.373) 132